5'-methylthioadenosine has been researched along with Carcinoma, Hepatocellular in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cetin Atalay, R; Guven, EB; Onder, T; Tuncbilek, M | 1 |
| Chu, YD; Huang, YH; Lai, HY; Liang, KH; Lin, YH; Pai, LM; Yeh, CT | 1 |
| Bosserhoff, AK; Czech, B; Dettmer, K; Hartmann, A; Hellerbrand, C; Kirovski, G; Oefner, PJ; Stevens, AP; Weiss, TS; Wild, P | 1 |
| Bae, W; Chen, L; Li, M; Lu, SC; Mato, JM; Ou, X; Runnegar, MT; Sadda, MR; Yang, H; Zeng, Y | 1 |
| Ansorena, E; Avila, MA; Berasain, C; García-Trevijano, ER; Iraburu, MJ; López Zabalza, MJ | 1 |
| Ansorena, E; Avila, MA; Chen, L; García-Trevijano, ER; Huang, ZZ; Iraburu, M; Lu, SC; Martínez-Chantar, ML; Mato, JM | 1 |
6 other study(ies) available for 5'-methylthioadenosine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(β-D-ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells.
Topics: Adenosine; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p15; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Purine Nucleosides; Retinoblastoma Protein; Structure-Activity Relationship | 2012 |
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caveolin 1; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Deoxyadenosines; Dioxygenases; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Prognosis; Promoter Regions, Genetic; S-Adenosylmethionine; Thionucleosides; Transplantation, Heterologous | 2019 |
Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
Topics: Aged; Carcinoma, Hepatocellular; Cell Line, Tumor; Deoxyadenosines; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Hepatic Stellate Cells; Humans; Liver Neoplasms; Male; Middle Aged; NF-kappa B; Purine-Nucleoside Phosphorylase; RNA, Messenger; Thionucleosides | 2011 |
S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S).
Topics: Acetylation; Animals; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Cells, Cultured; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histones; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Phosphoprotein Phosphatases; Phosphorylation; Promoter Regions, Genetic; Protein Isoforms; Protein Phosphatase 1; Proto-Oncogene Proteins c-bcl-2; S-Adenosylmethionine; Sarcoplasmic Reticulum; Thionucleosides; Tubercidin | 2004 |
Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Deoxyadenosines; Gene Expression Regulation; Hepatocytes; Humans; Male; MAP Kinase Kinase 4; Rats; Rats, Wistar; S-Adenosylmethionine; Signal Transduction; Thionucleosides; Transcription Factor AP-1 | 2006 |
S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cells, Cultured; Cytochrome c Group; Deoxyadenosines; Enzyme Activation; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Okadaic Acid; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; S-Adenosylmethionine; Species Specificity; Thionucleosides | 2002 |