5--amino-2--5--dideoxythymidine and Hypersensitivity--Delayed

5--amino-2--5--dideoxythymidine has been researched along with Hypersensitivity--Delayed* in 1 studies

Other Studies

1 other study(ies) available for 5--amino-2--5--dideoxythymidine and Hypersensitivity--Delayed

ArticleYear
Comparative effects of 5'-amino-5'-deoxythymidine, a new antiviral agent, and 5-iodo-2'-deoxyuridine on the immune response of mice. No immunosuppression with 5'-amino-5'-deoxythymidine.
    International journal of immunopharmacology, 1982, Volume: 4, Issue:6

    Immunological function was analyzed in mice that received daily inoculations of 5'-amino-5'-deoxythymidine (1000 mg/kg/day, i.p.) or 5-iodo-2'-deoxyuridine (100 mg/kg/day, i.p.) following antigenic stimulation. 5' Amino-5'-deoxythymidine did not suppress the development of: (1) delayed type hypersensitivity response to sheep red blood cells, (2) cell-mediated cytotoxicity response to allogeneic tumor cells, and (3) IgM and IgG antibody response to sheep red blood cells. In contrast 5-iodo-2'-deoxyuridine suppressed the development of all of these responses.

    Topics: Animals; Antiviral Agents; Cytotoxicity, Immunologic; Dideoxynucleosides; Erythrocytes; Female; Hypersensitivity, Delayed; Idoxuridine; Immunity; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Thymidine

1982