5'-(1,4-dihydro-1-methyl-3-pyridinylcarbonyl)-3'-azido-3'-deoxythymidine has been researched along with Acquired Immunodeficiency Syndrome in 2 studies
*Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, WR; Biegon, A; Brewster, ME; Harish, Z; Mizrachi, Y; Rubinstein, A | 1 |
| Balzarini, J; De Clercq, E; Kinjo, J; Lesiak, K; Torrence, PF | 1 |
2 other study(ies) available for 5'-(1,4-dihydro-1-methyl-3-pyridinylcarbonyl)-3'-azido-3'-deoxythymidine and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Improved brain delivery and in vitro activity of zidovudine through the use of a redox chemical delivery system.
Topics: Acquired Immunodeficiency Syndrome; Animals; Cells, Cultured; Dihydropyridines; Drug Delivery Systems; Humans; Lymphocytes; Male; Neurons; Prodrugs; Rats; Rats, Sprague-Dawley; Tissue Distribution; Zidovudine | 1995 |
AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become 'locked' in the central nervous system.
Topics: Acquired Immunodeficiency Syndrome; Animals; Brain; Cell Line; Chemical Phenomena; Chemistry; Dementia; Dihydropyridines; HIV; Humans; Male; Mice; Moloney murine sarcoma virus; Pharmaceutical Preparations; Prodrugs; Rats; Rats, Inbred Strains; Thymidine; Virus Replication; Zidovudine | 1988 |