5-(n,n-hexamethylene)amiloride has been researched along with Pancreatic Neoplasms in 1 studies
5-(N,N-hexamethylene)amiloride: inhibitor of Na+-H+ exchange; has anti-HIV-1 activity
5-(N,N-hexamethylene)amiloride : A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buckley, BJ | 1 |
| Aboelela, A | 1 |
| Minaei, E | 1 |
| Jiang, LX | 1 |
| Xu, Z | 1 |
| Ali, U | 1 |
| Fildes, K | 1 |
| Cheung, CY | 1 |
| Cook, SM | 1 |
| Johnson, DC | 1 |
| Bachovchin, DA | 1 |
| Cook, GM | 1 |
| Apte, M | 1 |
| Huang, M | 1 |
| Ranson, M | 1 |
| Kelso, MJ | 1 |
1 other study available for 5-(n,n-hexamethylene)amiloride and Pancreatic Neoplasms
| Article | Year |
|---|---|
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
Topics: Amiloride; Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Crystallography, X-Ray | 2018 |