5-(n,n-hexamethylene)amiloride has been researched along with Arrhythmias, Cardiac in 2 studies
5-(N,N-hexamethylene)amiloride: inhibitor of Na+-H+ exchange; has anti-HIV-1 activity
5-(N,N-hexamethylene)amiloride : A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In each case, reperfusion ventricular arrhythmias were reduced by 69-73% (p less than 0." | 5.28 | Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange. ( Coetzee, WA; Cragoe, EJ; Dennis, SC; Opie, LH, 1990) |
| "In each case, reperfusion ventricular arrhythmias were reduced by 69-73% (p less than 0." | 1.28 | Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange. ( Coetzee, WA; Cragoe, EJ; Dennis, SC; Opie, LH, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meiltz, A | 1 |
| Kucera, P | 1 |
| de Ribaupierre, Y | 1 |
| Raddatz, E | 1 |
| Dennis, SC | 1 |
| Coetzee, WA | 1 |
| Cragoe, EJ | 1 |
| Opie, LH | 1 |
2 other studies available for 5-(n,n-hexamethylene)amiloride and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Inhibition of bicarbonate transport protects embryonic heart against reoxygenation-induced dysfunction.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Arrhythmias, Cardiac | 1998 |
Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Buffers; Carrier Proteins; HEPES; In Vitro Techniques; Mal | 1990 |