Page last updated: 2024-10-21

5-(n,n-hexamethylene)amiloride and Arrhythmia

5-(n,n-hexamethylene)amiloride has been researched along with Arrhythmia in 2 studies

5-(N,N-hexamethylene)amiloride: inhibitor of Na+-H+ exchange; has anti-HIV-1 activity
5-(N,N-hexamethylene)amiloride : A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.

Research Excerpts

ExcerptRelevanceReference
"In each case, reperfusion ventricular arrhythmias were reduced by 69-73% (p less than 0."5.28Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange. ( Coetzee, WA; Cragoe, EJ; Dennis, SC; Opie, LH, 1990)
"In each case, reperfusion ventricular arrhythmias were reduced by 69-73% (p less than 0."1.28Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange. ( Coetzee, WA; Cragoe, EJ; Dennis, SC; Opie, LH, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meiltz, A1
Kucera, P1
de Ribaupierre, Y1
Raddatz, E1
Dennis, SC1
Coetzee, WA1
Cragoe, EJ1
Opie, LH1

Other Studies

2 other studies available for 5-(n,n-hexamethylene)amiloride and Arrhythmia

ArticleYear
Inhibition of bicarbonate transport protects embryonic heart against reoxygenation-induced dysfunction.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Arrhythmias, Cardiac

1998
Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange.
    Circulation research, 1990, Volume: 66, Issue:4

    Topics: Amiloride; Animals; Arrhythmias, Cardiac; Buffers; Carrier Proteins; HEPES; In Vitro Techniques; Mal

1990