5-(n,n-hexamethylene)amiloride has been researched along with Ache in 1 studies
5-(N,N-hexamethylene)amiloride: inhibitor of Na+-H+ exchange; has anti-HIV-1 activity
5-(N,N-hexamethylene)amiloride : A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of amiloride derivatives modified at the 5-position of the pyrazine ring were evaluated as inhibitors of acid-sensing ion channel-3 (ASIC3), a novel target for the treatment of chronic pain." | 3.75 | Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3). ( Bilodeau, MT; Bock, MG; Cato, MJ; Chang, RK; Cook, SP; Di Marco, CN; Dipardo, RM; Hartman, GD; Jovanovska, A; Kane, SA; Kuduk, SD; Leitl, M; Spencer, RH; Urban, MO, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuduk, SD | 1 |
| Di Marco, CN | 1 |
| Chang, RK | 1 |
| Dipardo, RM | 1 |
| Cook, SP | 1 |
| Cato, MJ | 1 |
| Jovanovska, A | 1 |
| Urban, MO | 1 |
| Leitl, M | 1 |
| Spencer, RH | 1 |
| Kane, SA | 1 |
| Bilodeau, MT | 1 |
| Hartman, GD | 1 |
| Bock, MG | 1 |
1 other study available for 5-(n,n-hexamethylene)amiloride and Ache
| Article | Year |
|---|---|
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Topics: Acid Sensing Ion Channels; Acidosis; Amiloride; Amines; Animals; Chemistry, Pharmaceutical; Drug Des | 2009 |