5-(4-acetamidophenyl)pyrazin-2(1h)-one has been researched along with Muscle Relaxation in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (88.89) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dent, G; Liebig, S; Magnussen, H; Rabe, KF; Schudt, C; Tenor, H | 1 |
| Berto, L; Bonnet, PA; Cortijo, J; Michel, A; Morcillo, EJ; Navarrete, C; Sanz, C; Villagrasa, V | 1 |
| Eckly-Michel, AE; Le Bec, A; Lugnier, C | 1 |
| Eckly-Michel, A; Lugnier, C; Martin, V | 1 |
| Benezech, V; Bonnet, P; Chapat, J; Deleuze-Masquefa, C; Elliott, K; Escale, R; Fabreguettes, J; Laurent, F; Michel, A; Parra, S; Pocock, T; Small, R; Subra, G; Vidal, J | 1 |
| Hall, IP; Hill, SJ | 1 |
| Barnette, MS; Barone, FC; Fowler, PJ; Grous, M; Ormsbee, HS; Price, WJ | 1 |
| Barnes, PJ; Rhoden, KJ | 1 |
| Barnette, MS; Grous, M; Ormsbee, HS; Torphy, TJ | 1 |
9 other study(ies) available for 5-(4-acetamidophenyl)pyrazin-2(1h)-one and Muscle Relaxation
| Article | Year |
|---|---|
Phosphodiesterase isozymes modulating inherent tone in human airways: identification and characterization.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adult; Aged; Bucladesine; Colforsin; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoenzymes; Lung; Lung Neoplasms; Male; Middle Aged; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nitroprusside; Purinones; Pyrazines; Pyridazines; Pyrrolidinones; Rolipram; Vital Capacity | 1993 |
Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Bronchi; Bronchodilator Agents; Calcium; Cardiotonic Agents; Cromakalim; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Humans; Imidazoles; In Vitro Techniques; Leukocyte Elastase; Leukotriene B4; Muscle Relaxation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoric Diester Hydrolases; Pyrazines; Pyrroles; Pyrrolidinones; Rolipram; Superoxides | 1996 |
Chelerythrine, a protein kinase C inhibitor, interacts with cyclic nucleotide phosphodiesterases.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Aorta; Benzophenanthridines; Cardiotonic Agents; Cattle; Drug Interactions; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Glycoproteins; Hydrolysis; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Pyrazines; Rats; Rats, Wistar | 1997 |
Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Aorta; Calcium; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Signal Transduction; Sulfonamides; Thionucleotides | 1997 |
Imidazo[1,2-a]quinoxalines: synthesis and cyclic nucleotide phosphodiesterase inhibitory activity.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Cardiotonic Agents; Cattle; Enzyme Inhibitors; Guinea Pigs; Inhibitory Concentration 50; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Muscle Relaxation; Muscle, Smooth; Nitriles; Pyrazines; Quinoxalines; Structure-Activity Relationship | 2001 |
Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone.
Topics: Animals; Bronchodilator Agents; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Isoenzymes; Methacholine Chloride; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rolipram; Trachea | 1992 |
Human lower oesophageal sphincter relaxation is associated with raised cyclic nucleotide content.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; Cyclic GMP; Electric Stimulation; Esophagogastric Junction; Humans; In Vitro Techniques; Muscle Relaxation; Nitroprusside; Nucleotides, Cyclic; Purinones; Pyrazines; Tetrodotoxin | 1991 |
Potentiation of nonadrenergic neural relaxation in guinea pig airways by a cyclic cAMP phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Potassium Chloride; Pyrazines; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide | 1990 |
Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Electric Stimulation; Enzyme Activation; Esophagogastric Junction; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Protein Kinases; Purinones; Pyrazines | 1990 |