Compounds > 5-(4-acetamidophenyl)pyrazin-2(1h)-one
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5-(4-acetamidophenyl)pyrazin-2(1h)-one and Muscle Contraction

5-(4-acetamidophenyl)pyrazin-2(1h)-one has been researched along with Muscle Contraction in 5 studies

*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnette, M; Grous, M1
Eckly, AE; Lugnier, C1
Barnes, PJ; Belvisi, MG; Bernareggi, MM; Giembycz, MA; Patel, H1
Barnes, PJ; Rhoden, KJ1
Barnette, MS; Grous, M; Ormsbee, HS; Torphy, TJ1

Other Studies

5 other study(ies) available for 5-(4-acetamidophenyl)pyrazin-2(1h)-one and Muscle Contraction

ArticleYear
Prevention by phosphodiesterase inhibitors of antigen-induced contraction of guinea-pig colonic smooth muscle.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antigens; Colon; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Immunization; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazines; Pyrrolidinones; Rolipram

1994
Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway.
    British journal of pharmacology, 1994, Volume: 113, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta, Thoracic; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Rats; Rats, Wistar; Rolipram

1994
Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.
    British journal of pharmacology, 1999, Volume: 128, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Animals; Antihypertensive Agents; Cardiotonic Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Histamine; In Vitro Techniques; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Parasympatholytics; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Trachea

1999
Potentiation of nonadrenergic neural relaxation in guinea pig airways by a cyclic cAMP phosphodiesterase inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Potassium Chloride; Pyrazines; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide

1990
Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Electric Stimulation; Enzyme Activation; Esophagogastric Junction; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Protein Kinases; Purinones; Pyrazines

1990