Compounds > 5-(3-4-dimethoxyphenyl)-2H-tetrazole

5-(3-4-dimethoxyphenyl)-2H-tetrazole and Edema

5-(3-4-dimethoxyphenyl)-2H-tetrazole has been researched along with Edema* in 1 studies

Other Studies

1 other study(ies) available for 5-(3-4-dimethoxyphenyl)-2H-tetrazole and Edema

Article	Year
Synthesis of 5-aryl-2H-tetrazoles, 5-aryl-2H-tetrazole-2-acetic acids, and [(4-phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic acids as possible superoxide scavengers and antiinflammatory agents. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 A series of 5-aryl-2H-tetrazoles, 5-aryl-2H-tetrazole-2-acetic acids, and [(4-phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic acids were synthesized and tested in vitro for superoxide scavenging activity, in vivo in the carrageenan-induced rat paw edema assay, and in the reverse passive Arthus reaction. The hydroxy-substituted compounds were effective as in vitro scavengers of superoxide but were not effective as in vivo antiinflammatory agents. Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthus Reaction; Azoles; Biological Assay; Edema; Indicators and Reagents; Magnetic Resonance Spectroscopy; Rats; Spectrophotometry, Infrared; Structure-Activity Relationship; Superoxides; Tetrazoles; Triazoles	1984

Article

Year

Synthesis of 5-aryl-2H-tetrazoles, 5-aryl-2H-tetrazole-2-acetic acids, and [(4-phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic acids as possible superoxide scavengers and antiinflammatory agents.

Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

A series of 5-aryl-2H-tetrazoles, 5-aryl-2H-tetrazole-2-acetic acids, and [(4-phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic acids were synthesized and tested in vitro for superoxide scavenging activity, in vivo in the carrageenan-induced rat paw edema assay, and in the reverse passive Arthus reaction. The hydroxy-substituted compounds were effective as in vitro scavengers of superoxide but were not effective as in vivo antiinflammatory agents.

Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthus Reaction; Azoles; Biological Assay; Edema; Indicators and Reagents; Magnetic Resonance Spectroscopy; Rats; Spectrophotometry, Infrared; Structure-Activity Relationship; Superoxides; Tetrazoles; Triazoles

1984