Compounds > 5-(3-3-dimethyl-1-triazeno)-1-methylimidazole-4-carboxamide

5-(3-3-dimethyl-1-triazeno)-1-methylimidazole-4-carboxamide and Lymphoma

5-(3-3-dimethyl-1-triazeno)-1-methylimidazole-4-carboxamide has been researched along with Lymphoma* in 2 studies

Other Studies

2 other study(ies) available for 5-(3-3-dimethyl-1-triazeno)-1-methylimidazole-4-carboxamide and Lymphoma

Article	Year
Chemical xenogenization of murine lymphoma cells with triazene derivatives: immunotoxicological studies. Cancer immunology, immunotherapy : CII, 1984, Volume: 17, Issue:3 Equitoxic doses of 5-(3-3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC) and aryl-triazene derivatives (compounds all capable of inducing a marked increase in murine tumor cell immunogenicity) were studied for their effects on the host immune system. At different times after drug exposure the animals were tested for allograft responses, competence in producing lymphocytes active in lethal graft-versus-host disease, delayed-type hypersensitivity, humoral antibody production, and mitogen responsiveness. While some of the aryl-triazenes tested (DM-COOK DM-NO2) showed a pattern of immunodepression similar to that of DTIC, others were less (MIC, MM-COOK, MM-Cl) or far less (DM-Cl, MM-NO2) active than DTIC in impairing host immunocompetence, although all retained or even augmented their ability to induce chemical xenogenization. Topics: Animals; Antibody Formation; Antigens, Neoplasm; Dacarbazine; Graft Rejection; Graft vs Host Disease; Graft vs Host Reaction; Hypersensitivity, Delayed; Immune Tolerance; Immunosuppressive Agents; Immunotherapy; Lymphocyte Activation; Lymphoma; Mice; Spleen; Structure-Activity Relationship; Triazenes	1984
[T cell lymphoma successfully treated with multiple chemotherapy including DTIC]. Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1983, Volume: 93, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Humans; Lymphoma; Middle Aged; Prednisolone; T-Lymphocytes; Vincristine	1983

Article

Year

Chemical xenogenization of murine lymphoma cells with triazene derivatives: immunotoxicological studies.

Cancer immunology, immunotherapy : CII, 1984, Volume: 17, Issue:3

Equitoxic doses of 5-(3-3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC) and aryl-triazene derivatives (compounds all capable of inducing a marked increase in murine tumor cell immunogenicity) were studied for their effects on the host immune system. At different times after drug exposure the animals were tested for allograft responses, competence in producing lymphocytes active in lethal graft-versus-host disease, delayed-type hypersensitivity, humoral antibody production, and mitogen responsiveness. While some of the aryl-triazenes tested (DM-COOK DM-NO2) showed a pattern of immunodepression similar to that of DTIC, others were less (MIC, MM-COOK, MM-Cl) or far less (DM-Cl, MM-NO2) active than DTIC in impairing host immunocompetence, although all retained or even augmented their ability to induce chemical xenogenization.

Topics: Animals; Antibody Formation; Antigens, Neoplasm; Dacarbazine; Graft Rejection; Graft vs Host Disease; Graft vs Host Reaction; Hypersensitivity, Delayed; Immune Tolerance; Immunosuppressive Agents; Immunotherapy; Lymphocyte Activation; Lymphoma; Mice; Spleen; Structure-Activity Relationship; Triazenes

1984

[T cell lymphoma successfully treated with multiple chemotherapy including DTIC].

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1983, Volume: 93, Issue:9

Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Humans; Lymphoma; Middle Aged; Prednisolone; T-Lymphocytes; Vincristine

1983