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4-vinyl-1-cyclohexene dioxide and FMR1-Related Primary Ovarian Insufficiency

4-vinyl-1-cyclohexene dioxide has been researched along with FMR1-Related Primary Ovarian Insufficiency in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (25.93)29.6817
2010's13 (48.15)24.3611
2020's7 (25.93)2.80

Authors

AuthorsStudies
Chen, W; Jin, X; Li, H; Wang, J; Wu, W; Yang, L; Zhou, Q1
Heo, JD; Joo, BS; Joo, JK; Lee, HJ; Park, MJ1
Contoreggi, NH; Glass, MJ; Iadecola, C; Marques-Lopes, J; Milner, TA; Ovalles, AC; Van Kempen, TA; Waters, EM1
Aydemir, S; Göker, A; Kiray, M; Mıcılı, SC; Özel, F1
Cao, LB; Chan, WY; Law, PW; Leung, CK; Liu, HB; Lu, G; Lv, Y; Ma, JL; Ng, CH1
Han, F; Kong, W; Liu, Q; Liu, Y; Shi, Y; Su, X; Wang, X; Yan, F1
Li, C; Qin, J; Wang, Y; Xia, Y; Xu, H; Xu, J1
Chen, J; Li, C; Qin, J; Tang, W; Tang, Y; Wang, W; Wang, Y; Xia, Y; Xu, H1
Ahn, C; Choi, KC; Dang, VH; Hyun, SH; Jeung, EB; Jung, EM; Kang, HY; Pham, TN; Tran, DN; Yoo, YM1
Anselmo-Franci, JA; Gregorio, T; Huber, DA; Lima, FB; Lino de Oliveira, C; Lorenzon, F; Simas, BB1
Balasubramaniam, V; Ferguson, M; Fernandes, RD; Hall, A; Lorenzen-Schmidt, I; Pyle, WG1
Cao, D; Li, M; Li, Y; Liu, J; Nie, G; Wu, S; Xie, L; Yang, H1
Anselmo-Franci, JA; Brandão, ML; Del-Ben, CM; Graeff, FG; Leite, CM; Lima, FB; Pestana-Oliveira, N; Reis, FM1
Ge, P; Han, D; Kuang, H; Li, J; Ren, Y; Xing, N; Zhu, L1
Ge, P; Han, D; Kuang, H; Li, J; Xing, N; Zhu, L1
Anselmo-Franci, JA; Barbosa, AM; Battiston, FG; Dos Santos, C; Leonel, ECR; Lima, FB; Rafacho, A; Sehnem, S; Taboga, SR1
Li, L; Ma, A; Pan, Q; Sun, Z; Wang, Z; Yan, D; Yang, Y; Zhang, T1
Brooks, HL; Christian, PJ; Hoyer, PB; Marion, SL; Rivera, Z1
Brooks, HL; Diamond-Stanic, MK; Hasty, AH; Hoyer, PB; Romero-Aleshire, MJ1
Barton, JK; Brewer, MA; Davis, JR; Hariri, LP; Hoyer, PB; Liebmann, ER; Marion, SL1
Milner, TA; Van Kempen, TA; Waters, EM1
Hoyer, PB; Kappeler, CJ1
Devine, PJ; Dyer, CA; Hoyer, PB; Mayer, LP1
Apopa, PL; Hu, X; Kan, YW; Ma, Q; Roberts, JR1
Brooks, HL; Cai, Q; Hoyer, PB; Keck, M; Romero-Aleshire, MJ1
Christian, PJ; Haas, JR; Hoyer, PB1
Bouxsein, ML; Christian, PJ; Funk, JL; Hoyer, PB; Rivera, Z; Van Alstine, WG; Wright, LE1

Reviews

2 review(s) available for 4-vinyl-1-cyclohexene dioxide and FMR1-Related Primary Ovarian Insufficiency

ArticleYear
Accelerated ovarian failure: a novel, chemically induced animal model of menopause.
    Brain research, 2011, Mar-16, Volume: 1379

    Topics: Animals; Cyclohexenes; Female; Humans; Menopause; Models, Animal; Ovariectomy; Postmenopause; Primary Ovarian Insufficiency; Time Factors; Vinyl Compounds

2011
4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity.
    Systems biology in reproductive medicine, 2012, Volume: 58, Issue:1

    Topics: Animals; Apoptosis; Cyclohexenes; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Humans; Mice; Models, Animal; Occupational Diseases; Occupational Exposure; Ovarian Follicle; Phosphorylation; Primary Ovarian Insufficiency; Proto-Oncogene Proteins c-kit; Rats; Risk Assessment; Species Specificity; Tissue Culture Techniques; Toxicity Tests; Vinyl Compounds

2012

Other Studies

25 other study(ies) available for 4-vinyl-1-cyclohexene dioxide and FMR1-Related Primary Ovarian Insufficiency

ArticleYear
4-vinylcyclohexene diepoxide induces premature ovarian insufficiency in rats by triggering the autophagy of granule cells through regulating miR-144.
    Journal of reproductive immunology, 2023, Volume: 157

    Topics: Animals; Autophagy; Female; Humans; MicroRNAs; Primary Ovarian Insufficiency; Proto-Oncogene Proteins c-akt; Rats

2023
Timing of hormone therapy and its association with cardiovascular risk and metabolic parameters in 4-vinylcyclohexene diepoxide-induced primary ovarian insufficiency mouse model.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2023, Aug-12, Volume: 39, Issue:1

    Topics: Animals; Cardiovascular Diseases; Cholesterol; Cytokines; Disease Models, Animal; Estradiol; Female; Heart Disease Risk Factors; Humans; Mice; Primary Ovarian Insufficiency; Risk Factors

2023
Plasma Membrane Affiliated AMPA GluA1 in Estrogen Receptor β-containing Paraventricular Hypothalamic Neurons Increases Following Hypertension in a Mouse Model of Post-menopause.
    Neuroscience, 2019, 12-15, Volume: 423

    Topics: Angiotensin II; Animals; Cell Membrane; Cyclohexenes; Estrogen Receptor beta; Female; Hypertension; Male; Mice; Neurons; Paraventricular Hypothalamic Nucleus; Postmenopause; Primary Ovarian Insufficiency; Receptors, AMPA; Vinyl Compounds

2019
Protective effect of alpha lipoic acid on 4-vinylcyclohexene diepoxide induced primary ovarian failure in female rats.
    Taiwanese journal of obstetrics & gynecology, 2020, Volume: 59, Issue:2

    Topics: Animals; Antioxidants; Cyclohexenes; Female; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Protective Agents; Rats; Thioctic Acid; Uterus; Vinyl Compounds

2020
Systemic changes in a mouse model of VCD-induced premature ovarian failure.
    Life sciences, 2020, Dec-01, Volume: 262

    Topics: Animals; Bone Density; Cyclohexenes; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Female; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Ovarian Follicle; Primary Ovarian Insufficiency; Vinyl Compounds

2020
Effect of Jiajian Guishen Formula on the senescence-associated heterochromatic foci in mouse ovaria after induction of premature ovarian aging by the endocrine-disrupting agent 4-vinylcyclohexene diepoxide.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Aging; Animals; Anti-Mullerian Hormone; Cellular Senescence; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Cyclohexenes; Cytokines; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Endocrine Disruptors; Estradiol; Estrogens; Estrous Cycle; Female; Follicle Stimulating Hormone; Heterochromatin; Histones; HMGA1a Protein; HMGA2 Protein; Luteinizing Hormone; Medicine, Chinese Traditional; Mice, Inbred ICR; Ovary; Primary Ovarian Insufficiency; Vinyl Compounds

2021
Effects of low intensity pulsed ultrasound on expression of B-cell lymphoma-2 and BCL2-Associated X in premature ovarian failure mice induced by 4-vinylcyclohexene diepoxide.
    Reproductive biology and endocrinology : RB&E, 2021, Jul-20, Volume: 19, Issue:1

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Cyclohexenes; Female; Mice; Mice, Inbred C57BL; Primary Ovarian Insufficiency; Proto-Oncogene Proteins c-bcl-2; Ultrasonic Therapy; Ultrasonic Waves; Vinyl Compounds

2021
Low-Intensity Pulsed Ultrasound Promotes Repair of 4-Vinylcyclohexene Diepoxide-Induced Premature Ovarian Insufficiency in SD Rats.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2022, 02-03, Volume: 77, Issue:2

    Topics: Animals; Cyclohexenes; Female; Male; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Ultrasonic Waves; Vinyl Compounds

2022
Depletion of follicles accelerated by combined exposure to phthalates and 4-vinylcyclohexene diepoxide, leading to premature ovarian failure in rats.
    Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 80

    Topics: Animals; Anti-Mullerian Hormone; Basic Helix-Loop-Helix Transcription Factors; Cyclohexenes; Drug Synergism; Endocrine Disruptors; Estrous Cycle; Female; Ovarian Follicle; Phthalic Acids; Primary Ovarian Insufficiency; Rats, Sprague-Dawley; Vinyl Compounds

2018
Ovarian failure induced by 4-vinylcyclohexene diepoxide worsens the autonomic cardiovascular response to chronic unpredictable stress in rats.
    Life sciences, 2019, Jun-01, Volume: 226

    Topics: Animals; Autonomic Nervous System; Baroreflex; Cardiovascular System; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Menopause; Ovarian Follicle; Ovary; Perimenopause; Primary Ovarian Insufficiency; Rats; Rats, Wistar; Stress, Psychological; Vinyl Compounds

2019
Cardiac changes during the peri-menopausal period in a VCD-induced murine model of ovarian failure.
    Acta physiologica (Oxford, England), 2019, Volume: 227, Issue:1

    Topics: Animals; Carcinogens; Cyclohexenes; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation; Heart; Menopause; Mice; Myofibrils; Ovary; Primary Ovarian Insufficiency; Transforming Growth Factor beta1; Ventricular Function, Left; Vinyl Compounds

2019
Huyang yangkun formula protects against 4-Vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats via the Hippo-JAK2/STAT3 signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 116

    Topics: Animals; Anti-Mullerian Hormone; Cluster Analysis; Cyclohexenes; Disease Models, Animal; Drugs, Chinese Herbal; Female; Gene Ontology; Janus Kinase 2; Kidney; Liver; Models, Biological; Ovarian Follicle; Primary Ovarian Insufficiency; Protective Agents; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Reference Standards; Signal Transduction; STAT3 Transcription Factor; Vinyl Compounds

2019
Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats.
    Psychoneuroendocrinology, 2014, Volume: 49

    Topics: Animals; Anxiety; Corticosterone; Cyclohexenes; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrous Cycle; Female; Follicle Stimulating Hormone; Maze Learning; Ovarian Follicle; Perimenopause; Primary Ovarian Insufficiency; Progesterone; Rats; Testosterone; Vinyl Compounds

2014
Preventive effect of American ginseng against premature ovarian failure in a rat model.
    Drug development research, 2014, Volume: 75, Issue:8

    Topics: Animals; Cyclohexenes; Disease Models, Animal; Female; Gene Expression Regulation; Hormones; Panax; Plant Extracts; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Vinyl Compounds

2014
American ginseng regulates gene expression to protect against premature ovarian failure in rats.
    BioMed research international, 2015, Volume: 2015

    Topics: 12E7 Antigen; Animals; Antigens, CD; Cell Adhesion Molecules; Cyclohexenes; Dinoprostone; Female; Follicle Stimulating Hormone, Human; Gene Expression Regulation; Humans; Luteinizing Hormone; Panax; Plant Extracts; Primary Ovarian Insufficiency; Rats; Vinyl Compounds

2015
Glucose homeostasis in rats treated with 4-vinylcyclohexene diepoxide is not worsened by dexamethasone treatment.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 165, Issue:Pt B

    Topics: Adipose Tissue; Aging; Animals; Blood Glucose; Cellular Senescence; Cyclohexenes; Dexamethasone; Drug Interactions; Female; Glucocorticoids; Glucose; Glucose Tolerance Test; Glycogen; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Liver; Ovarian Follicle; Ovary; Primary Ovarian Insufficiency; Rats; Rats, Wistar; Steroids; Vinyl Compounds

2017
The comparison of animal models for premature ovarian failure established by several different source of inducers.
    Regulatory toxicology and pharmacology : RTP, 2016, Volume: 81

    Topics: Animals; Busulfan; Cisplatin; Cyclohexenes; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Galactose; Glycosides; Mice; Mice, Inbred Strains; Ovary; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Tripterygium; Vinyl Compounds

2016
Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice.
    Biology of reproduction, 2009, Volume: 80, Issue:2

    Topics: Androstenedione; Animals; Carcinogens; Cyclohexenes; Cytochrome P-450 Enzyme System; Estrous Cycle; Female; Follicle Stimulating Hormone; Gene Expression Regulation, Enzymologic; Gonadal Steroid Hormones; Hydroxysteroid Dehydrogenases; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Ovary; Primary Ovarian Insufficiency; Vinyl Compounds

2009
Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Abdominal Fat; Animals; Blood Glucose; Cholesterol; Cyclohexenes; Dietary Fats; Disease Models, Animal; Disease Progression; Estrogen Replacement Therapy; Fatty Acids, Nonesterified; Female; Insulin; Insulin Resistance; Menopause; Metabolic Syndrome; Mice; Ovary; Primary Ovarian Insufficiency; Time Factors; Vinyl Compounds; Weight Gain

2009
Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis.
    Cancer biology & therapy, 2010, Sep-01, Volume: 10, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclohexenes; Disease Models, Animal; Female; Lasers; Ovarian Neoplasms; Ovary; Primary Ovarian Insufficiency; Rats; Rats, Inbred F344; Sex Cord-Gonadal Stromal Tumors; Spectrometry, Fluorescence; Tomography, Optical Coherence; Vinyl Compounds

2010
The follicle-deplete mouse ovary produces androgen.
    Biology of reproduction, 2004, Volume: 71, Issue:1

    Topics: Androgens; Animals; Caspase 3; Caspases; Cells, Cultured; Cyclohexanes; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Follicle Stimulating Hormone; Hormones; Liver; Luteinizing Hormone; Mice; Mice, Inbred Strains; Organ Size; Ovarian Follicle; Ovary; Primary Ovarian Insufficiency; Steroids; Uterus; Vinyl Compounds

2004
Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice.
    Molecular and cellular biology, 2006, Volume: 26, Issue:3

    Topics: Animals; Apoptosis; Cyclohexanes; Cyclohexenes; Epoxide Hydrolases; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Inactivation, Metabolic; Mice; Mice, Mutant Strains; Mutation; NF-E2-Related Factor 2; Ovarian Follicle; Oxidative Stress; Primary Ovarian Insufficiency; Proteasome Endopeptidase Complex; Signal Transduction; Vinyl Compounds

2006
Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; Blood Glucose; Cell Proliferation; Cyclohexenes; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Female; Hormones; Humans; Immunohistochemistry; Kidney Cortex; Menopause; Mice; Mice, Inbred Strains; Primary Ovarian Insufficiency; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; RNA; Vinyl Compounds; Weight Gain

2007
Effects of impending ovarian failure induced by 4-vinylcyclohexene diepoxide on fertility in C57BL/6 female mice.
    Comparative medicine, 2007, Volume: 57, Issue:5

    Topics: Animals; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Fertility; Infertility, Female; Mice; Mice, Inbred C57BL; Ovarian Follicle; Perimenopause; Postmenopause; Pregnancy; Pregnancy Rate; Primary Ovarian Insufficiency; Vinyl Compounds

2007
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2008, Volume: 23, Issue:8

    Topics: Androstenedione; Animals; Body Weight; Bone and Bones; Bone Density; Cyclohexenes; Estradiol; Female; Mice; Mice, Inbred C57BL; Organ Size; Ovariectomy; Primary Ovarian Insufficiency; Time Factors; Vinyl Compounds

2008