Page last updated: 2024-08-18

4-vinyl-1-cyclohexene dioxide and Disease Models, Animal

4-vinyl-1-cyclohexene dioxide has been researched along with Disease Models, Animal in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (23.08)29.6817
2010's16 (61.54)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Heo, JD; Joo, BS; Joo, JK; Lee, HJ; Park, MJ1
Han, SH; Jeon, S; Jeong, HJ; Kim, D; Kim, DI; Liu, QF1
Cao, LB; Chan, WY; Law, PW; Leung, CK; Liu, HB; Lu, G; Lv, Y; Ma, JL; Ng, CH1
Han, F; Kong, W; Liu, Q; Liu, Y; Shi, Y; Su, X; Wang, X; Yan, F1
Joo, BS; Joo, JK; Kim, CW; Kim, KH; Kim, YH; Lee, HJ; Park, MJ; Yang, SW1
Anselmo-Franci, JA; Gregorio, T; Huber, DA; Lima, FB; Lino de Oliveira, C; Lorenzon, F; Simas, BB1
Cao, D; Li, M; Li, Y; Liu, J; Nie, G; Wu, S; Xie, L; Yang, H1
Barton, JK; Brewer, MA; Hoyer, PB; Marion, SL; Sen, N; Watson, J1
Anselmo-Franci, JA; Brandão, ML; Del-Ben, CM; Graeff, FG; Leite, CM; Lima, FB; Pestana-Oliveira, N; Reis, FM1
Bhowmik, M; Pottoo, FH; Vohora, D1
Ge, P; Han, D; Kuang, H; Li, J; Ren, Y; Xing, N; Zhu, L1
Brooks, HL; Konhilas, JP; Pollow, DP; Romero-Aleshire, MJ; Sanchez, JN1
Fan, GW; Liu, W; Wang, LY; Xing, XX1
Glass, MJ; Iadecola, C; Israilov, S; Marques-Lopes, J; Milner, TA; Pickel, VM; Tesfaye, E; Van Kempen, TA; Wang, G; Waters, EM1
Brooks, HL; Hoyer, PB; Pollow, DP1
Asare, PF; Fan, G; Gao, X; Li, L; Liu, E; Su, L; Wang, L; Xing, X; Yu, B; Zhu, Y1
Li, L; Ma, A; Pan, Q; Sun, Z; Wang, Z; Yan, D; Yang, Y; Zhang, T1
Barton, JK; Bedrnicek, JB; Brewer, MA; Christian, PJ; Davis, JR; Hoyer, PB; Marion, SL1
Lorenzana, A; Schauwecker, PE; Wood, RI1
Adams, MR; Appt, SE; Arifin, EA; Christian, PJ; Cline, JM; Goode, AK; Hoyer, PB; Isom, S; Kaplan, JR; Kock, ND; Muhammad, FS1
Brooks, HL; Diamond-Stanic, MK; Hasty, AH; Hoyer, PB; Romero-Aleshire, MJ1
Barton, JK; Brewer, MA; Davis, JR; Hariri, LP; Hoyer, PB; Liebmann, ER; Marion, SL1
Devine, PJ; Ethier, JF; Laviolette, LA; Senterman, MK; Vanderhyden, BC1
Appt, SE; Chen, H; Clarkson, TB; Ethun, KF; Goode, AK; Hoyer, PB; Kaplan, JR; Kock, ND; May, MC; Persyn, JT; Sen, N; Vail, NK1
Devine, PJ; Dyer, CA; Hoyer, PB; Mayer, LP1
Christian, PJ; Haas, JR; Hoyer, PB1

Reviews

1 review(s) available for 4-vinyl-1-cyclohexene dioxide and Disease Models, Animal

ArticleYear
The VCD Mouse Model of Menopause and Perimenopause for the Study of Sex Differences in Cardiovascular Disease and the Metabolic Syndrome.
    Physiology (Bethesda, Md.), 2016, Volume: 31, Issue:4

    Topics: Animals; Cardiovascular Diseases; Cyclohexenes; Diabetic Nephropathies; Disease Models, Animal; Female; Humans; Male; Menopause; Metabolic Syndrome; Mice; Ovary; Perimenopause; Sex Characteristics; Vinyl Compounds

2016

Other Studies

25 other study(ies) available for 4-vinyl-1-cyclohexene dioxide and Disease Models, Animal

ArticleYear
Timing of hormone therapy and its association with cardiovascular risk and metabolic parameters in 4-vinylcyclohexene diepoxide-induced primary ovarian insufficiency mouse model.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2023, Aug-12, Volume: 39, Issue:1

    Topics: Animals; Cardiovascular Diseases; Cholesterol; Cytokines; Disease Models, Animal; Estradiol; Female; Heart Disease Risk Factors; Humans; Mice; Primary Ovarian Insufficiency; Risk Factors

2023
A Modified Formulation of Sutaehwan Ameliorates Menopausal Anxiety, Depression and Heart Hypertrophy in the VCD-Induced Menopausal Mouse Model.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:9

    Topics: Animals; Anxiety; Cardiomegaly; Cyclohexenes; Depression; Disease Models, Animal; Female; Humans; MCF-7 Cells; Medicine, Korean Traditional; Menopause; Mice, Inbred C57BL; Plant Extracts; Vinyl Compounds

2019
Systemic changes in a mouse model of VCD-induced premature ovarian failure.
    Life sciences, 2020, Dec-01, Volume: 262

    Topics: Animals; Bone Density; Cyclohexenes; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Female; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Ovarian Follicle; Primary Ovarian Insufficiency; Vinyl Compounds

2020
Effect of Jiajian Guishen Formula on the senescence-associated heterochromatic foci in mouse ovaria after induction of premature ovarian aging by the endocrine-disrupting agent 4-vinylcyclohexene diepoxide.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Aging; Animals; Anti-Mullerian Hormone; Cellular Senescence; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Cyclohexenes; Cytokines; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Endocrine Disruptors; Estradiol; Estrogens; Estrous Cycle; Female; Follicle Stimulating Hormone; Heterochromatin; Histones; HMGA1a Protein; HMGA2 Protein; Luteinizing Hormone; Medicine, Chinese Traditional; Mice, Inbred ICR; Ovary; Primary Ovarian Insufficiency; Vinyl Compounds

2021
Effects of coenzyme Q10 on ovarian surface epithelium-derived ovarian stem cells and ovarian function in a 4-vinylcyclohexene diepoxide-induced murine model of ovarian failure.
    Reproductive biology and endocrinology : RB&E, 2021, Apr-22, Volume: 19, Issue:1

    Topics: Animals; Cells, Cultured; Cyclohexenes; Disease Models, Animal; Epithelium; Female; In Vitro Oocyte Maturation Techniques; Mice; Mice, Inbred C57BL; Oocytes; Ovarian Diseases; Ovary; Stem Cells; Ubiquinone; Vinyl Compounds

2021
Ovarian failure induced by 4-vinylcyclohexene diepoxide worsens the autonomic cardiovascular response to chronic unpredictable stress in rats.
    Life sciences, 2019, Jun-01, Volume: 226

    Topics: Animals; Autonomic Nervous System; Baroreflex; Cardiovascular System; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Menopause; Ovarian Follicle; Ovary; Perimenopause; Primary Ovarian Insufficiency; Rats; Rats, Wistar; Stress, Psychological; Vinyl Compounds

2019
Huyang yangkun formula protects against 4-Vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats via the Hippo-JAK2/STAT3 signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 116

    Topics: Animals; Anti-Mullerian Hormone; Cluster Analysis; Cyclohexenes; Disease Models, Animal; Drugs, Chinese Herbal; Female; Gene Ontology; Janus Kinase 2; Kidney; Liver; Models, Biological; Ovarian Follicle; Primary Ovarian Insufficiency; Protective Agents; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Reference Standards; Signal Transduction; STAT3 Transcription Factor; Vinyl Compounds

2019
7,12-dimethylbenz[a]anthracene-induced malignancies in a mouse model of menopause.
    Comparative medicine, 2013, Volume: 63, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Cyclohexenes; Disease Models, Animal; Female; Immunohistochemistry; Mice; Ovarian Neoplasms; Ovary; Postmenopause; Time Factors; Vinyl Compounds

2013
Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats.
    Psychoneuroendocrinology, 2014, Volume: 49

    Topics: Animals; Anxiety; Corticosterone; Cyclohexenes; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrous Cycle; Female; Follicle Stimulating Hormone; Maze Learning; Ovarian Follicle; Perimenopause; Primary Ovarian Insufficiency; Progesterone; Rats; Testosterone; Vinyl Compounds

2014
Raloxifene protects against seizures and neurodegeneration in a mouse model mimicking epilepsy in postmenopausal woman.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Dec-18, Volume: 65

    Topics: Animals; Bone Density; Cyclohexenes; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Kainic Acid; Mice; Neurodegenerative Diseases; Neurons; Postmenopause; Raloxifene Hydrochloride; Seizures; Transforming Growth Factor beta3; Vinyl Compounds

2014
Preventive effect of American ginseng against premature ovarian failure in a rat model.
    Drug development research, 2014, Volume: 75, Issue:8

    Topics: Animals; Cyclohexenes; Disease Models, Animal; Female; Gene Expression Regulation; Hormones; Panax; Plant Extracts; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Vinyl Compounds

2014
ANG II-induced hypertension in the VCD mouse model of menopause is prevented by estrogen replacement during perimenopause.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Dec-15, Volume: 309, Issue:12

    Topics: Angiotensin II; Animals; Aquaporin 2; Arterial Pressure; Cell Proliferation; Cyclohexenes; Disease Models, Animal; Drug Administration Schedule; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Injections, Intraperitoneal; Kidney Cortex; Menopause; Mice, Inbred C57BL; Perimenopause; Risk Factors; Time Factors; Vinyl Compounds

2015
Conditions and possible mechanisms of VCD-induced ovarian failure.
    Alternatives to laboratory animals : ATLA, 2015, Volume: 43, Issue:6

    Topics: Animals; Apoptosis; Cyclohexenes; Disease Models, Animal; Female; Humans; Mice; Ovarian Follicle; Perimenopause; Rats; Signal Transduction; Vinyl Compounds

2015
Redistribution of NMDA Receptors in Estrogen-Receptor-β-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure.
    Neuroendocrinology, 2017, Volume: 104, Issue:3

    Topics: Angiotensin II; Animals; Blood Pressure; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Green Fluorescent Proteins; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Nerve Tissue Proteins; Neurons; Ovarian Diseases; Paraventricular Hypothalamic Nucleus; Reactive Oxygen Species; Receptors, Estrogen; Receptors, N-Methyl-D-Aspartate; Vinyl Compounds

2017
Danzhi Qing'e (DZQE) activates AMPK pathway and regulates lipid metabolism in a rat model of perimenopausal hyperlipidaemia.
    Experimental physiology, 2016, 11-01, Volume: 101, Issue:11

    Topics: Acetyl-CoA Carboxylase; Adenylate Kinase; Animals; Cyclohexenes; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Estradiol; Female; Follicle Stimulating Hormone; Hyperlipidemias; Lipid Metabolism; Luteinizing Hormone; Ovarian Follicle; Perimenopause; Rats; Rats, Wistar; Vinyl Compounds

2016
The comparison of animal models for premature ovarian failure established by several different source of inducers.
    Regulatory toxicology and pharmacology : RTP, 2016, Volume: 81

    Topics: Animals; Busulfan; Cisplatin; Cyclohexenes; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Galactose; Glycosides; Mice; Mice, Inbred Strains; Ovary; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Tripterygium; Vinyl Compounds

2016
Ovarian neoplasm development by 7,12-dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian failure.
    Gynecologic oncology, 2009, Volume: 112, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclohexenes; Disease Models, Animal; Drug Administration Schedule; Female; Ovarian Follicle; Ovarian Neoplasms; Rats; Rats, Inbred F344; Vinyl Compounds

2009
Neuroprotection against excitotoxic brain injury in mice after ovarian steroid depletion.
    Brain research, 2009, Apr-10, Volume: 1265

    Topics: Administration, Cutaneous; Animals; Brain; Carcinogens; Cell Death; Cyclohexenes; Disease Models, Animal; Estrogens; Excitatory Amino Acid Agonists; Female; Hippocampus; Histology; Injections, Intraperitoneal; Injections, Subcutaneous; Kainic Acid; Mice; Mice, Inbred Strains; Neurons; Neuroprotective Agents; Ovarian Follicle; Ovariectomy; Ovary; Seizures; Vinyl Compounds

2009
Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes.
    Comparative medicine, 2009, Volume: 59, Issue:1

    Topics: Aging; Animals; Apoptosis; Body Weight; Carcinogens; Cyclohexenes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Injections, Intraperitoneal; Muscle, Skeletal; Myositis; Ovarian Follicle; Ovary; Rats; Rats, Sprague-Dawley; Sexual Maturation; Vinyl Compounds

2009
Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Abdominal Fat; Animals; Blood Glucose; Cholesterol; Cyclohexenes; Dietary Fats; Disease Models, Animal; Disease Progression; Estrogen Replacement Therapy; Fatty Acids, Nonesterified; Female; Insulin; Insulin Resistance; Menopause; Metabolic Syndrome; Mice; Ovary; Primary Ovarian Insufficiency; Time Factors; Vinyl Compounds; Weight Gain

2009
Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis.
    Cancer biology & therapy, 2010, Sep-01, Volume: 10, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclohexenes; Disease Models, Animal; Female; Lasers; Ovarian Neoplasms; Ovary; Primary Ovarian Insufficiency; Rats; Rats, Inbred F344; Sex Cord-Gonadal Stromal Tumors; Spectrometry, Fluorescence; Tomography, Optical Coherence; Vinyl Compounds

2010
Induction of a menopausal state alters the growth and histology of ovarian tumors in a mouse model of ovarian cancer.
    Menopause (New York, N.Y.), 2011, Volume: 18, Issue:5

    Topics: Animals; Cell Line, Tumor; Cyclohexenes; Disease Models, Animal; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Menopause; Mice; Mice, Transgenic; Ovarian Follicle; Ovarian Neoplasms; Sertoli Cell Tumor; Simian virus 40; Vinyl Compounds

2011
Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis).
    Comparative medicine, 2010, Volume: 60, Issue:5

    Topics: Animals; Anti-Mullerian Hormone; Cyclohexenes; Disease Models, Animal; Female; Macaca fascicularis; Ovarian Diseases; Ovarian Follicle; Ovary; Sexual Development; Vinyl Compounds

2010
The follicle-deplete mouse ovary produces androgen.
    Biology of reproduction, 2004, Volume: 71, Issue:1

    Topics: Androgens; Animals; Caspase 3; Caspases; Cells, Cultured; Cyclohexanes; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Follicle Stimulating Hormone; Hormones; Liver; Luteinizing Hormone; Mice; Mice, Inbred Strains; Organ Size; Ovarian Follicle; Ovary; Primary Ovarian Insufficiency; Steroids; Uterus; Vinyl Compounds

2004
Effects of impending ovarian failure induced by 4-vinylcyclohexene diepoxide on fertility in C57BL/6 female mice.
    Comparative medicine, 2007, Volume: 57, Issue:5

    Topics: Animals; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Fertility; Infertility, Female; Mice; Mice, Inbred C57BL; Ovarian Follicle; Perimenopause; Postmenopause; Pregnancy; Pregnancy Rate; Primary Ovarian Insufficiency; Vinyl Compounds

2007