Page last updated: 2024-09-03

4-s-cysteaminylphenol and Melanoma

4-s-cysteaminylphenol has been researched along with Melanoma in 11 studies

*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's7 (63.64)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hasegawa, K; Inoue, S; Ito, S; Olivares, C; Otake, H; Solano, F; Wakamatsu, K; Yukitake, J1
Ito, S; Ito, Y; Jimbow, K; Kasuga, T; Miura, S1
Fujita, K; Hasegawa, K; Inoue, S; Ito, S; Jiménez-Cervantes, C; Ozeki, H; Solano, F; Wakamatsu, K1
Hasegawa, K; Inoue, S; Ishiguro, I; Ito, S; Ozeki, H; Wakamatsu, K1
Jimbow, K1
Bloomer, WD; Prezioso, JA; Wang, N1
Bloomer, WD; Epperly, MW; Prezioso, JA; Wang, N1
Fujita, K; Inoue, S; Ito, S; Jimbow, K; Wakamatsu, K1
Ito, S; Jimbow, K; Pankovich, JM1
Engelhardt, R; Ito, S; Jimbow, K; Yamada, K1
Ito, Y; Jimbow, K1

Other Studies

11 other study(ies) available for 4-s-cysteaminylphenol and Melanoma

ArticleYear
Synthesis and selective in vitro anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol.
    Melanoma research, 2003, Volume: 13, Issue:6

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cysteamine; Glutathione; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Melanoma; Melanoma, Experimental; Mice; Models, Chemical; Monophenol Monooxygenase; Phenols; Stereoisomerism; Time Factors; Tyrosine

2003
[Utilization of melanin precursors for experimental chemotherapy of malignant melanoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:10

    Topics: Animals; Catecholamines; Cysteamine; Cysteine; Dihydroxyphenylalanine; Melanins; Melanocytes; Melanoma; Mice; Monophenol Monooxygenase; Neoplasms, Experimental; Skin Neoplasms

1984
Antimelanoma effect of 4-S-cysteaminylcatechol, an activated form of 4-S-cysteaminylphenol.
    Cancer research, 1995, Jun-15, Volume: 55, Issue:12

    Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Division; Cell Line; Cell Survival; Cysteamine; Dose-Response Relationship, Drug; Humans; Kinetics; Levodopa; Melanoma; Melanoma, Experimental; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Monophenol Monooxygenase; Oxidation-Reduction; Oxidoreductases; Proteins; Tumor Cells, Cultured

1995
Dihydro-1,4-benzothiazine-6,7-dione, the ultimate toxic metabolite of 4-S-cysteaminylphenol and 4-S-cysteaminylcatechol.
    Biochemical pharmacology, 1997, May-15, Volume: 53, Issue:10

    Topics: Animals; Antineoplastic Agents; Catalase; Chromatography, High Pressure Liquid; Cysteamine; Drug Screening Assays, Antitumor; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Spectrophotometry, Atomic; Superoxide Dismutase; Thiazines; Tumor Cells, Cultured

1997
[Development of targeted chemoradiotherapy for malignant melanoma by exploitation of metabolic pathway].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Agents; Cysteamine; Cysteine; DNA Damage; Humans; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oxidative Stress; Phenols; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Tyrosine

1998
Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Agents; Cell Division; Cell-Free System; Cysteamine; DNA; Humans; Kinetics; Leucovorin; Melanoma; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Tetrazolium Salts; Theophylline; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured

1992
Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells.
    Cancer letters, 1992, Mar-31, Volume: 63, Issue:1

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cysteamine; Drug Synergism; Humans; Melanoma; Methionine Sulfoximine; Monophenol Monooxygenase; Phenols; Theophylline; Time Factors; Tumor Cells, Cultured

1992
Mechanism of growth inhibition of melanoma cells by 4-S-cysteaminylphenol and its analogues.
    Biochemical pharmacology, 1990, Mar-15, Volume: 39, Issue:6

    Topics: Antineoplastic Agents; Cell Division; Chromatography, High Pressure Liquid; Cysteamine; Humans; Melanins; Melanoma; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Monophenol Monooxygenase; Phenylthiourea; Semicarbazides; Tumor Cells, Cultured

1990
4-S-cysteaminylphenol and its analogues as substrates for tyrosinase and monoamine oxidase.
    Pigment cell research, 1990, Volume: 3, Issue:3

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Basidiomycota; Cell Line; Cysteamine; Kinetics; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monophenol Monooxygenase; Oxidation-Reduction; Pigmentation; Quinones

1990
Selective cytotoxicity of a phenolic melanin precursor, 4-S-cysteaminylphenol, on in vitro melanoma cells.
    Biochemical pharmacology, 1989, Jul-01, Volume: 38, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cysteamine; DNA Replication; Humans; Kinetics; Melanins; Melanoma; Melanoma, Experimental; Mice; Tumor Cells, Cultured

1989
Selective cytotoxicity of 4-S-cysteaminylphenol on follicular melanocytes of the black mouse: rational basis for its application to melanoma chemotherapy.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Animals; Cell Survival; Cysteamine; Hair; Melanins; Melanocytes; Melanoma; Mice; Mice, Inbred A; Mice, Inbred C57BL; Microscopy, Electron; Monophenol Monooxygenase

1987