4-phenylbutyric acid has been researched along with Stomach Neoplasms in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Stomach Neoplasms: Tumors or cancer of the STOMACH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The growth inhibitory effect of PBA on gastric cancer cells is associated with alteration of the cell cycle." | 1.38 | Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with cell cycle arrest. ( Deng, HX; Guo, JM; Li, LZ; Lou, WZ; Song, MW; Sun, XY; Tao, J; Xiao, BX, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, X | 1 |
| Zheng, C | 1 |
| Li, C | 1 |
| Hou, K | 1 |
| Wang, X | 1 |
| Yang, Z | 1 |
| Liu, C | 1 |
| Liu, Y | 1 |
| Che, X | 1 |
| Qu, X | 1 |
| Saito, Y | 1 |
| Suzuki, H | 1 |
| Tsugawa, H | 1 |
| Nakagawa, I | 1 |
| Matsuzaki, J | 1 |
| Kanai, Y | 1 |
| Hibi, T | 1 |
| Li, LZ | 1 |
| Deng, HX | 1 |
| Lou, WZ | 1 |
| Sun, XY | 1 |
| Song, MW | 1 |
| Tao, J | 1 |
| Xiao, BX | 1 |
| Guo, JM | 1 |
3 other studies available for 4-phenylbutyric acid and Stomach Neoplasms
| Article | Year |
|---|---|
4-Phenybutyric acid promotes gastric cancer cell migration via histone deacetylase inhibition-mediated HER3/HER4 up-regulation.
Topics: Acetylation; Apoptosis; Cell Line, Tumor; Cell Movement; Histone Acetyltransferases; Histone Deacety | 2018 |
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.
Topics: Alu Elements; Apoptosis; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Chromoso | 2009 |
Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with cell cycle arrest.
Topics: Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Growt | 2012 |