4-phenylbutyric acid has been researched along with Spinal Cord Injuries in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Zheng, S | 1 |
| Gu, Y | 1 |
| Zhou, L | 1 |
| Lin, B | 1 |
| Liu, W | 1 |
| Fan, H | 1 |
| Tang, HB | 1 |
| Kang, J | 1 |
| Shan, L | 1 |
| Song, H | 1 |
| Zhu, K | 1 |
| Wang, J | 1 |
| Ju, G | 1 |
| Wang, YZ | 1 |
| Zhou, Y | 1 |
| Wu, Y | 1 |
| Liu, Y | 1 |
| He, Z | 1 |
| Zou, S | 1 |
| Wang, Q | 1 |
| Li, J | 1 |
| Zheng, Z | 1 |
| Chen, J | 1 |
| Wu, F | 1 |
| Gong, F | 1 |
| Zhang, H | 1 |
| Xu, H | 1 |
| Xiao, J | 1 |
3 other studies available for 4-phenylbutyric acid and Spinal Cord Injuries
| Article | Year |
|---|---|
4-PBA Enhances Autophagy by Inhibiting Endoplasmic Reticulum Stress in Recombinant Human Beta Nerve Growth Factor-Induced PC12 cells After Mechanical Injury via PI3K/AKT/mTOR Signaling Pathway.
Topics: Animals; Autophagy; Chromones; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Hu | 2020 |
Involvement of endoplasmic reticulum stress in the necroptosis of microglia/macrophages after spinal cord injury.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic R | 2015 |
The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury.
Topics: Animals; Autophagy; Capillary Permeability; Cells, Cultured; Chloroquine; Endoplasmic Reticulum Stre | 2017 |