4-phenylbutyric acid has been researched along with Sleep Wake Disorders in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokoi, N | 1 |
| Fukata, Y | 1 |
| Kase, D | 1 |
| Miyazaki, T | 1 |
| Jaegle, M | 1 |
| Ohkawa, T | 1 |
| Takahashi, N | 1 |
| Iwanari, H | 1 |
| Mochizuki, Y | 1 |
| Hamakubo, T | 1 |
| Imoto, K | 1 |
| Meijer, D | 1 |
| Watanabe, M | 1 |
| Fukata, M | 1 |
1 other study available for 4-phenylbutyric acid and Sleep Wake Disorders
| Article | Year |
|---|---|
Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.
Topics: ADAM Proteins; Animals; Disease Models, Animal; Epilepsy, Frontal Lobe; Genetic Predisposition to Di | 2015 |