4-phenylbutyric acid has been researched along with Retinitis in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Retinitis: Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic retinopathy is a chronic low-grade inflammatory disease; however, the mechanisms remain elusive." | 1.35 | Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy. ( Li, J; Wang, JJ; Wang, M; Yu, Q; Zhang, SX, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Wang, JJ | 1 |
| Yu, Q | 1 |
| Wang, M | 1 |
| Zhang, SX | 1 |
1 other study available for 4-phenylbutyric acid and Retinitis
| Article | Year |
|---|---|
Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy.
Topics: Animals; Base Sequence; Cells, Cultured; Diabetic Retinopathy; DNA Primers; Endoplasmic Reticulum; E | 2009 |