4-phenylbutyric acid has been researched along with Respiratory Distress Syndrome in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ERS is involved in ARDS-related right ventricular dysfunction." | 1.51 | [Protective effect of sodium 4-phenylbutyrate on rats with acute respiratory distress syndrome related right ventricular dysfunction by alleviating endoplasmic reticulum stress]. ( Ma, S; Wang, Y; Xu, C; Yao, J; Zhou, Y; Zuo, X, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, S | 1 |
| Zuo, X | 1 |
| Wang, Y | 1 |
| Yao, J | 1 |
| Zhou, Y | 1 |
| Xu, C | 1 |
1 other study available for 4-phenylbutyric acid and Respiratory Distress Syndrome
| Article | Year |
|---|---|
[Protective effect of sodium 4-phenylbutyrate on rats with acute respiratory distress syndrome related right ventricular dysfunction by alleviating endoplasmic reticulum stress].
Topics: Animals; Antineoplastic Agents; Endoplasmic Reticulum Stress; Male; Phenylbutyrates; Rats; Rats, Spr | 2019 |