4-phenylbutyric acid has been researched along with Pulmonary Consumption in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mily, A | 1 |
| Rekha, RS | 1 |
| Kamal, SM | 1 |
| Arifuzzaman, AS | 1 |
| Rahim, Z | 1 |
| Khan, L | 1 |
| Haq, MA | 1 |
| Zaman, K | 1 |
| Bergman, P | 1 |
| Brighenti, S | 1 |
| Gudmundsson, GH | 1 |
| Agerberth, B | 1 |
| Raqib, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Trial of Oral Phenylbutyrate and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis in Bangladesh: a Pilot Study[NCT01580007] | Phase 2 | 288 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for 4-phenylbutyric acid and Pulmonary Consumption
| Article | Year |
|---|---|
Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial.
Topics: Administration, Oral; Adult; Antimicrobial Cationic Peptides; Antitubercular Agents; C-Reactive Prot | 2015 |