4-phenylbutyric acid and Polycystic Kidney, Autosomal Dominant

4-phenylbutyric acid has been researched along with Polycystic Kidney, Autosomal Dominant in 1 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.

Research

Studies (1)

Authors

Other Studies

1 other study available for 4-phenylbutyric acid and Polycystic Kidney, Autosomal Dominant