Page last updated: 2024-11-02

4-phenylbutyric acid and Muscle Contraction

4-phenylbutyric acid has been researched along with Muscle Contraction in 2 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlisle, RE1
Werner, KE1
Yum, V1
Lu, C1
Tat, V1
Memon, M1
No, Y1
Ask, K1
Dickhout, JG1
Begam, M1
Abro, VM1
Mueller, AL1
Roche, JA1

Other Studies

2 other studies available for 4-phenylbutyric acid and Muscle Contraction

ArticleYear
Endoplasmic reticulum stress inhibition reduces hypertension through the preservation of resistance blood vessel structure and function.
    Journal of hypertension, 2016, Volume: 34, Issue:8

    Topics: Animals; Blood Pressure; Endoplasmic Reticulum Stress; Hypertension; Male; Mesenteric Arteries; Musc

2016
Sodium 4-phenylbutyrate reduces myofiber damage in a mouse model of Duchenne muscular dystrophy.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016, Volume: 41, Issue:10

    Topics: Animals; Hindlimb; Histone Deacetylase Inhibitors; Injections, Intraperitoneal; Leg Injuries; Macrop

2016