4-phenylbutyric acid has been researched along with Mouth Neoplasms in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qian, K | 1 |
| Sun, L | 1 |
| Zhou, G | 1 |
| Ge, H | 1 |
| Meng, Y | 1 |
| Li, J | 1 |
| Li, X | 1 |
| Fang, X | 1 |
| Chung, YL | 1 |
| Lee, MY | 1 |
| Pui, NN | 1 |
2 other studies available for 4-phenylbutyric acid and Mouth Neoplasms
| Article | Year |
|---|---|
Sodium Phenylbutyrate Inhibits Tumor Growth and the Epithelial-Mesenchymal Transition of Oral Squamous Cell Carcinoma In Vitro and In Vivo.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchyma | 2018 |
Epigenetic therapy using the histone deacetylase inhibitor for increasing therapeutic gain in oral cancer: prevention of radiation-induced oral mucositis and inhibition of chemical-induced oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Administration, Oral; Animals; Antineoplastic Agents; | 2009 |