4-phenylbutyric acid has been researched along with Metabolic Acidosis in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yung, HW | 1 |
| Alnæs-Katjavivi, P | 1 |
| Jones, CJ | 1 |
| El-Bacha, T | 1 |
| Golic, M | 1 |
| Staff, AC | 1 |
| Burton, GJ | 1 |
1 other study available for 4-phenylbutyric acid and Metabolic Acidosis
| Article | Year |
|---|---|
Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants.
Topics: Acidosis; Adult; Antioxidants; Ascorbic Acid; Blood Glucose; Blotting, Western; Cell Line; Diabetes, | 2016 |