4-phenylbutyric acid has been researched along with Mental Disorders in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, M | 1 |
| Yamamoto, H | 1 |
| Miyagi, T | 1 |
| Seki, T | 1 |
| Tanaka, S | 1 |
| Hide, I | 1 |
| Sakai, N | 1 |
1 other study available for 4-phenylbutyric acid and Mental Disorders
| Article | Year |
|---|---|
Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells.
Topics: Animals; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; COS Cells; Dose-Response Relationship | 2013 |