Page last updated: 2024-11-02

4-phenylbutyric acid and MODS

4-phenylbutyric acid has been researched along with MODS in 1 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hong, YP1
Deng, WH1
Guo, WY1
Shi, Q1
Zhao, L1
You, YD1
Mei, FC1
Zhou, Y1
Wang, CY1
Chen, C1
Yu, J1
Wang, WX1

Other Studies

1 other study available for 4-phenylbutyric acid and MODS

ArticleYear
Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 11-01, Volume: 315, Issue:5

    Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Interleukin-1beta; Male; Multiple Organ Failure; P

2018