4-phenylbutyric acid has been researched along with Lymphoproliferative Disorders in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Lymphoproliferative Disorders: Disorders characterized by proliferation of lymphoid tissue, general or unspecified.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bueno, MJ | 1 |
| Pérez de Castro, I | 1 |
| Gómez de Cedrón, M | 1 |
| Santos, J | 1 |
| Calin, GA | 1 |
| Cigudosa, JC | 1 |
| Croce, CM | 1 |
| Fernández-Piqueras, J | 1 |
| Malumbres, M | 1 |
1 other study available for 4-phenylbutyric acid and Lymphoproliferative Disorders
| Article | Year |
|---|---|
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.
Topics: 3' Untranslated Regions; Animals; Azacitidine; Cell Line, Tumor; Cell Proliferation; Chromosomes, Hu | 2008 |