Page last updated: 2024-11-02

4-phenylbutyric acid and Lupus Nephritis

4-phenylbutyric acid has been researched along with Lupus Nephritis in 1 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonnemaison, ML1
Marks-Nelson, ES1
Boesen, EI1

Other Studies

1 other study available for 4-phenylbutyric acid and Lupus Nephritis

ArticleYear
Sodium 4-phenylbutyrate treatment protects against renal injury in NZBWF1 mice.
    Clinical science (London, England : 1979), 2019, 01-31, Volume: 133, Issue:2

    Topics: Albuminuria; Animals; Apoptosis; Crosses, Genetic; Disease Models, Animal; Endoplasmic Reticulum Cha

2019