4-phenylbutyric acid has been researched along with Lipodystrophy in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Lipodystrophy: A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guridi, M | 1 |
| Tintignac, LA | 1 |
| Lin, S | 1 |
| Kupr, B | 1 |
| Castets, P | 1 |
| Rüegg, MA | 1 |
1 other study available for 4-phenylbutyric acid and Lipodystrophy
| Article | Year |
|---|---|
Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.
Topics: Animals; Endoplasmic Reticulum Stress; Fatty Acids; Female; Fibroblast Growth Factors; Glucose; Insu | 2015 |