4-phenylbutyric acid has been researched along with Lipid Metabolism Disorders in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Lipid Metabolism Disorders: Pathological conditions resulting from abnormal anabolism or catabolism of lipids in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methimazole (MMI) was applied to construct a noninvasive SCH mouse model." | 1.43 | Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism. ( Bo, T; Chen, W; Ding, S; Gao, L; Li, C; Li, Y; Liu, X; Wang, L; Wu, K; Xu, C; Zhao, J; Zhou, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, L | 1 |
| Ding, S | 1 |
| Li, Y | 1 |
| Wang, L | 1 |
| Chen, W | 1 |
| Bo, T | 1 |
| Wu, K | 1 |
| Li, C | 1 |
| Liu, X | 1 |
| Zhao, J | 1 |
| Xu, C | 1 |
| Gao, L | 1 |
1 other study available for 4-phenylbutyric acid and Lipid Metabolism Disorders
| Article | Year |
|---|---|
Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism.
Topics: Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Hypothyroidism; Lipid Metabol | 2016 |