4-phenylbutyric acid has been researched along with Intracranial Hemorrhages in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Intracranial Hemorrhages: Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murray, LS | 1 |
| Lu, Y | 1 |
| Taggart, A | 1 |
| Van Regemorter, N | 1 |
| Vilain, C | 1 |
| Abramowicz, M | 1 |
| Kadler, KE | 1 |
| Van Agtmael, T | 1 |
1 other study available for 4-phenylbutyric acid and Intracranial Hemorrhages
| Article | Year |
|---|---|
Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke.
Topics: Apoptosis; Basement Membrane; Brain Diseases; Cell Proliferation; Cells, Cultured; Collagen Type IV; | 2014 |