4-phenylbutyric acid has been researched along with Injury, Myocardial Reperfusion in 7 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfur dioxide has recently been found to be produced endogenously in the cardiovascular system and have important positive biological effects." | 1.37 | Effect of sulfur dioxide preconditioning on rat myocardial ischemia/reperfusion injury by inducing endoplasmic reticulum stress. ( Du, JB; Huang, XM; Jin, HF; Li, XY; Ochs, T; Tang, CS; Wang, XB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Q | 1 |
| Thompson, J | 1 |
| Hu, Y | 1 |
| Lesnefsky, EJ | 1 |
| Guo, J | 1 |
| Zhu, J | 1 |
| Ma, L | 1 |
| Shi, H | 1 |
| Hu, J | 1 |
| Zhang, S | 1 |
| Hou, L | 1 |
| Xu, F | 1 |
| An, Y | 1 |
| Yu, H | 1 |
| Ge, J | 1 |
| Mariángelo, JIE | 1 |
| Román, B | 1 |
| Silvestri, MA | 1 |
| Salas, M | 1 |
| Vittone, L | 1 |
| Said, M | 1 |
| Mundiña-Weilenmann, C | 1 |
| Jian, L | 2 |
| Lu, Y | 2 |
| Lu, S | 2 |
| Lu, C | 2 |
| Takatori, O | 1 |
| Usui, S | 1 |
| Okajima, M | 1 |
| Kaneko, S | 1 |
| Ootsuji, H | 1 |
| Takashima, SI | 1 |
| Kobayashi, D | 1 |
| Murai, H | 1 |
| Furusho, H | 1 |
| Takamura, M | 1 |
| Wang, XB | 1 |
| Huang, XM | 1 |
| Ochs, T | 1 |
| Li, XY | 1 |
| Jin, HF | 1 |
| Tang, CS | 1 |
| Du, JB | 1 |
7 other studies available for 4-phenylbutyric acid and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Reversing mitochondrial defects in aged hearts: role of mitochondrial calpain activation.
Topics: Age Factors; Animals; Calpain; Cysteine Proteinase Inhibitors; Dipeptides; Disease Models, Animal; E | 2022 |
Chronic Kidney Disease Exacerbates Myocardial Ischemia Reperfusion Injury: Role of Endoplasmic Reticulum Stress-Mediated Apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Ret | 2018 |
Chemical chaperones improve the functional recovery of stunned myocardium by attenuating the endoplasmic reticulum stress.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cholagogues and Choleretics; Disease Models, Animal; Endo | 2020 |
Chemical chaperone 4-phenylbutyric acid protects H9c2 cardiomyocytes from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis.
Topics: Animals; Apoptosis; Cell Line; Endoplasmic Reticulum Stress; Molecular Chaperones; Muscle Proteins; | 2016 |
Sodium 4-Phenylbutyrate Attenuates Myocardial Reperfusion Injury by Reducing the Unfolded Protein Response.
Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression Regulation; Male; Mice, Inbred C57BL; My | 2017 |
Chemical Chaperone 4-Phenylbutyric Acid Reduces Cardiac Ischemia/Reperfusion Injury by Alleviating Endoplasmic Reticulum Stress and Oxidative Stress.
Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Endoplasmic Reticulum Stress; Heart; Heart Fun | 2016 |
Effect of sulfur dioxide preconditioning on rat myocardial ischemia/reperfusion injury by inducing endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Caspase 12; Creatine Kinase; Dithiothreitol; Endoplasmic Reticulum; Heart; Heat- | 2011 |