4-phenylbutyric acid has been researched along with Impaired Glucose Tolerance in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| de Pablo, S | 1 |
| Rodríguez-Comas, J | 1 |
| Díaz-Catalán, D | 1 |
| Alcarraz-Vizán, G | 1 |
| Castaño, C | 1 |
| Moreno-Vedia, J | 1 |
| Montane, J | 1 |
| Parrizas, M | 1 |
| Servitja, JM | 1 |
| Novials, A | 1 |
| Townsend, LK | 1 |
| Medak, KD | 1 |
| Peppler, WT | 1 |
| Meers, GM | 1 |
| Rector, RS | 1 |
| LeBlanc, PJ | 1 |
| Wright, DC | 1 |
| da-Silva, WS | 1 |
| Ribich, S | 1 |
| Arrojo e Drigo, R | 1 |
| Castillo, M | 1 |
| Patti, ME | 1 |
| Bianco, AC | 1 |
3 other studies available for 4-phenylbutyric acid and Impaired Glucose Tolerance
| Article | Year |
|---|---|
4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity.
Topics: Amyloid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal | 2021 |
High-saturated-fat diet-induced obesity causes hepatic interleukin-6 resistance via endoplasmic reticulum stress.
Topics: Animals; Diet, High-Fat; Dietary Fats; Endoplasmic Reticulum Stress; Glucose; Glucose Intolerance; H | 2019 |
The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.
Topics: Adipocytes, Brown; Animals; Cell Line; Cells, Cultured; Dietary Fats; Energy Metabolism; Gene Expres | 2011 |