Page last updated: 2024-11-02

4-phenylbutyric acid and Idiopathic Hypoparathyroidism

4-phenylbutyric acid has been researched along with Idiopathic Hypoparathyroidism in 1 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Idiopathic Hypoparathyroidism: A condition of low or absent PTH level and HYPOCALCEMIA. It usually occurs as part of an autoimmune syndrome.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Datta, R1
Waheed, A1
Shah, GN1
Sly, WS1

Other Studies

1 other study available for 4-phenylbutyric acid and Idiopathic Hypoparathyroidism

ArticleYear
Signal sequence mutation in autosomal dominant form of hypoparathyroidism induces apoptosis that is corrected by a chemical chaperone.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-11, Volume: 104, Issue:50

    Topics: Amino Acid Sequence; Apoptosis; Biological Transport; Cell Line; Cysteine; Endoplasmic Reticulum; Ge

2007