4-phenylbutyric acid has been researched along with Hyperplasia in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neointima formation was increased by 54." | 1.40 | Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury. ( Furuhashi, M; Fuseya, T; Hoshina, K; Inoue, K; Ishimura, S; Kokubu, N; Mita, T; Miura, T; Watanabe, Y; Yoshida, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishimura, S | 1 |
| Furuhashi, M | 1 |
| Mita, T | 1 |
| Fuseya, T | 1 |
| Watanabe, Y | 1 |
| Hoshina, K | 1 |
| Kokubu, N | 1 |
| Inoue, K | 1 |
| Yoshida, H | 1 |
| Miura, T | 1 |
1 other study available for 4-phenylbutyric acid and Hyperplasia
| Article | Year |
|---|---|
Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury.
Topics: Animals; Becaplermin; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; DNA-Bind | 2014 |