4-phenylbutyric acid has been researched along with Hyperglycemia, Postprandial in 6 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Hyperglycemia, Postprandial: Abnormally high BLOOD GLUCOSE level after a meal.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| de Pablo, S | 1 |
| Rodríguez-Comas, J | 1 |
| Díaz-Catalán, D | 1 |
| Alcarraz-Vizán, G | 1 |
| Castaño, C | 1 |
| Moreno-Vedia, J | 1 |
| Montane, J | 1 |
| Parrizas, M | 1 |
| Servitja, JM | 1 |
| Novials, A | 1 |
| Kato, A | 1 |
| Tatsumi, Y | 1 |
| Yako, H | 1 |
| Sango, K | 1 |
| Himeno, T | 1 |
| Kondo, M | 1 |
| Kato, Y | 1 |
| Kamiya, H | 1 |
| Nakamura, J | 1 |
| Kato, K | 1 |
| Xu, TY | 1 |
| Chen, RH | 1 |
| Wang, P | 2 |
| Zhang, RY | 1 |
| Ke, SF | 1 |
| Miao, CY | 1 |
| Tang, C | 1 |
| Koulajian, K | 1 |
| Schuiki, I | 1 |
| Zhang, L | 1 |
| Desai, T | 1 |
| Ivovic, A | 1 |
| Robson-Doucette, C | 1 |
| Wheeler, MB | 1 |
| Minassian, B | 1 |
| Volchuk, A | 1 |
| Giacca, A | 1 |
| Li, X | 1 |
| Xu, C | 1 |
| Yang, P | 1 |
| Fu, SH | 1 |
| Chen, ST | 1 |
| Hsu, BR | 1 |
6 other studies available for 4-phenylbutyric acid and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity.
Topics: Amyloid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal | 2021 |
Recurrent short-term hypoglycemia and hyperglycemia induce apoptosis and oxidative stress via the ER stress response in immortalized adult mouse Schwann (IMS32) cells.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Endoplasmic Reticulum Stress; Glucose; Hyperglycemia; | 2019 |
4-Phenyl butyric acid does not generally reduce glucose levels in rodent models of diabetes.
Topics: Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; | 2010 |
Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress.
Topics: Animals; Antioxidants; Cyclic N-Oxides; Endoplasmic Reticulum Stress; Female; Glucose; Hyperglycemia | 2012 |
c-Jun NH2-terminal kinase 1/2 and endoplasmic reticulum stress as interdependent and reciprocal causation in diabetic embryopathy.
Topics: Animals; Apoptosis; Biomarkers; Caspase 3; Caspase 8; Diabetes Mellitus, Experimental; Endoplasmic R | 2013 |
Attenuation of primary nonfunction for syngeneic islet graft using sodium 4-phenylbutyrate.
Topics: Animals; Diabetes Mellitus, Type 1; Hyperglycemia; Islets of Langerhans Transplantation; Mice; Mice, | 2005 |