4-phenylbutyric acid has been researched along with Hepatitis C in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, K | 1 |
| Lee, YS | 1 |
| Jeong, S | 1 |
| Kim, D | 1 |
| Chon, S | 1 |
| Pak, YK | 1 |
| Kim, S | 1 |
| Ha, J | 1 |
| Kang, I | 1 |
| Choe, W | 1 |
| Song, K | 1 |
| Han, C | 1 |
| Zhang, J | 1 |
| Lu, D | 1 |
| Dash, S | 1 |
| Feitelson, M | 1 |
| Lim, K | 1 |
| Wu, T | 1 |
| Huang, H | 1 |
| Kang, R | 1 |
| Wang, J | 1 |
| Luo, G | 1 |
| Yang, W | 1 |
| Zhao, Z | 1 |
3 other studies available for 4-phenylbutyric acid and Hepatitis C
| Article | Year |
|---|---|
A Small Molecule, 4-Phenylbutyric Acid, Suppresses HCV Replication via Epigenetically Induced Hepatic Hepcidin.
Topics: Animals; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression; Hepacivirus; Hepatitis C; Hepcidins | 2020 |
Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.
Topics: Azacitidine; Carcinoma, Hepatocellular; Decitabine; Epigenesis, Genetic; Hep G2 Cells; Hepatitis C; | 2013 |
Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Autophagy; Autophagy-Related Protein-1 Ho | 2013 |