4-phenylbutyric acid has been researched along with Hemochromatosis in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Hemochromatosis: A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Almeida, SF | 1 |
| Picarote, G | 1 |
| Fleming, JV | 1 |
| Carmo-Fonseca, M | 1 |
| Azevedo, JE | 1 |
| de Sousa, M | 1 |
1 other study available for 4-phenylbutyric acid and Hemochromatosis
| Article | Year |
|---|---|
Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation.
Topics: Cell Line; Endoplasmic Reticulum; Flow Cytometry; Hemochromatosis; Hemochromatosis Protein; Histocom | 2007 |