4-phenylbutyric acid has been researched along with Hearing Loss in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Hearing Loss: A general term for the complete or partial loss of the ability to hear from one or both ears.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, B | 1 |
| Zheng, T | 1 |
| Yan, C | 1 |
| Wang, W | 1 |
| Zhang, J | 1 |
| Zhang, L | 2 |
| Hu, J | 1 |
| Wan, Y | 1 |
| Zhang, M | 1 |
| Zheng, Q | 1 |
1 other study available for 4-phenylbutyric acid and Hearing Loss
| Article | Year |
|---|---|
Chemical chaperone 4-phenylbutyrate prevents hearing loss and cochlear hair cell death in Cdh23erl/erl mutant mice.
Topics: Animals; Apoptosis; Cadherins; Cell Death; Deafness; Endoplasmic Reticulum Stress; Hair Cells, Audit | 2019 |