4-phenylbutyric acid has been researched along with Fatty Liver, Nonalcoholic in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Non-alcoholic fatty liver disease (NAFLD) is a rapidly growing health threat that has previously been associated with lipogenesis." | 1.43 | Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells. ( Chen, SC; Hu, ZJ; Ren, LP; Song, GY; Sun, LN; Yu, X; Zhang, P; Zhang, XM, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ai, Y | 1 |
| Sun, Z | 1 |
| Peng, C | 1 |
| Liu, L | 1 |
| Xiao, X | 1 |
| Li, J | 1 |
| He, L | 1 |
| Yuan, FH | 1 |
| Chen, T | 1 |
| Huang, Q | 1 |
| Wang, Y | 1 |
| Liu, ZG | 1 |
| Ren, LP | 1 |
| Yu, X | 1 |
| Song, GY | 1 |
| Zhang, P | 1 |
| Sun, LN | 1 |
| Chen, SC | 1 |
| Hu, ZJ | 1 |
| Zhang, XM | 1 |
3 other studies available for 4-phenylbutyric acid and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Homocysteine Induces Hepatic Steatosis Involving ER Stress Response in High Methionine Diet-Fed Mice.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cells, Cultured; Endoplasmic Reticulum Stress | 2017 |
ER stress-mediated cell damage contributes to the release of EDA
Topics: Adult; Cell Death; Cell Line; Endoplasmic Reticulum Stress; Female; Fibronectins; Hep G2 Cells; Hepa | 2017 |
Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells.
Topics: Activating Transcription Factor 4; Endoplasmic Reticulum Stress; Fructose; Gene Expression; Gene Sil | 2016 |