4-phenylbutyric acid has been researched along with Epidermolysis Bullosa in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Epidermolysis Bullosa: Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spörrer, M | 1 |
| Prochnicki, A | 1 |
| Tölle, RC | 1 |
| Nyström, A | 1 |
| Esser, PR | 1 |
| Homberg, M | 1 |
| Athanasiou, I | 1 |
| Zingkou, E | 1 |
| Schilling, A | 1 |
| Gerum, R | 1 |
| Thievessen, I | 1 |
| Winter, L | 1 |
| Bruckner-Tuderman, L | 1 |
| Fabry, B | 1 |
| Magin, TM | 1 |
| Dengjel, J | 1 |
| Schröder, R | 1 |
| Kiritsi, D | 1 |
1 other study available for 4-phenylbutyric acid and Epidermolysis Bullosa
| Article | Year |
|---|---|
Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders.
Topics: Animals; Apoptosis; Biomarkers; Biopsy; Cell Adhesion; Cell Communication; Cell Line; Cytoskeleton; | 2019 |