4-phenylbutyric acid has been researched along with Endotoxin Shock in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis and septic shock are the common complications in ICUs." | 1.43 | 4-Phenylbutyric Acid Reveals Good Beneficial Effects on Vital Organ Function via Anti-Endoplasmic Reticulum Stress in Septic Rats. ( Chen, X; Lan, D; Li, T; Liu, L; Wu, H; Wu, Y; Yang, G; Zang, J; Zhu, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, L | 1 |
| Wu, H | 1 |
| Zang, J | 1 |
| Yang, G | 1 |
| Zhu, Y | 1 |
| Wu, Y | 1 |
| Chen, X | 1 |
| Lan, D | 1 |
| Li, T | 1 |
1 other study available for 4-phenylbutyric acid and Endotoxin Shock
| Article | Year |
|---|---|
4-Phenylbutyric Acid Reveals Good Beneficial Effects on Vital Organ Function via Anti-Endoplasmic Reticulum Stress in Septic Rats.
Topics: Animals; Apoptosis; Caspases; Cytokines; Disease Models, Animal; Endoplasmic Reticulum Stress; Femal | 2016 |