4-phenylbutyric acid has been researched along with Diathesis in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "RETRACTED: Obesity is a significant risk factor for acute respiratory distress syndrome." | 1.46 | Obesity-Induced Endoplasmic Reticulum Stress Causes Lung Endothelial Dysfunction and Promotes Acute Lung Injury. ( Guo, Z; Kallen, CB; Li, J; Naik, UP; Romero, F; Shah, D; Summer, R; Sun, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bose, A | 1 |
| Kasle, G | 1 |
| Jana, R | 1 |
| Maulik, M | 1 |
| Thomas, D | 1 |
| Mulchandani, V | 1 |
| Mukherjee, P | 1 |
| Koval, M | 1 |
| Das Sarma, J | 1 |
| Shah, D | 1 |
| Romero, F | 1 |
| Guo, Z | 1 |
| Sun, J | 1 |
| Li, J | 1 |
| Kallen, CB | 1 |
| Naik, UP | 1 |
| Summer, R | 1 |
| Chan, JY | 1 |
| Luzuriaga, J | 1 |
| Bensellam, M | 1 |
| Biden, TJ | 1 |
| Laybutt, DR | 1 |
3 other studies available for 4-phenylbutyric acid and Diathesis
| Article | Year |
|---|---|
Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cell Communication; Cell Line, Tumor; Connexin 43; Disease Su | 2023 |
Obesity-Induced Endoplasmic Reticulum Stress Causes Lung Endothelial Dysfunction and Promotes Acute Lung Injury.
Topics: Activating Transcription Factor 6; Acute Lung Injury; Animals; Cell Adhesion Molecules; Dietary Fats | 2017 |
Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes.
Topics: Animals; Antioxidants; Apoptosis Regulatory Proteins; Cytokines; Diabetes Mellitus, Type 2; Disease | 2013 |