Page last updated: 2024-11-02

4-phenylbutyric acid and Cyst

4-phenylbutyric acid has been researched along with Cyst in 2 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Research Excerpts

ExcerptRelevanceReference
" In this study, the amoebicidal activity of different generation cationic carbosilane dendrons derived with 4-phenylbutyric acid was demonstrated against Acanthamoeba polyphaga and Acanthamoeba griffini trophozoites and cysts."8.12Amoebicidal activity of cationic carbosilane dendrons derived with 4-phenylbutyric acid against Acanthamoeba griffini and Acanthamoeba polyphaga trophozoites and cysts. ( Gómez, R; Gómez-Casanova, N; Heredero-Bermejo, I; López-Barona, P; Lozano-Cruz, T; Martín-Pérez, T; Ortega, P; Pérez-Serrano, J; Verdú-Expósito, C, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
López-Barona, P1
Verdú-Expósito, C1
Martín-Pérez, T1
Gómez-Casanova, N1
Lozano-Cruz, T1
Ortega, P1
Gómez, R1
Pérez-Serrano, J1
Heredero-Bermejo, I1
Tietz Bogert, PS1
Huang, BQ1
Gradilone, SA1
Masyuk, TV1
Moulder, GL1
Ekker, SC1
Larusso, NF1

Other Studies

2 other studies available for 4-phenylbutyric acid and Cyst

ArticleYear
Amoebicidal activity of cationic carbosilane dendrons derived with 4-phenylbutyric acid against Acanthamoeba griffini and Acanthamoeba polyphaga trophozoites and cysts.
    Scientific reports, 2022, Sep-02, Volume: 12, Issue:1

    Topics: Acanthamoeba; Acanthamoeba castellanii; Amebicides; Animals; Cations; Cysts; Dendrimers; Humans; Phe

2022
The zebrafish as a model to study polycystic liver disease.
    Zebrafish, 2013, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents; Calcium-Binding Proteins; Cysts; Disease Models, Animal; DNA Helicas

2013