4-phenylbutyric acid has been researched along with Contracture in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Joint contracture is a common complication for people with joint immobility that involves fibrosis structural alteration in the joint capsule." | 1.48 | Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model. ( He, R; Jiang, S; Liang, T; Lu, Y; Ren, J; Wang, K; Wang, Z; Xiao, D; Yi, X; Zhu, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, S | 1 |
| He, R | 1 |
| Zhu, L | 1 |
| Liang, T | 1 |
| Wang, Z | 1 |
| Lu, Y | 1 |
| Ren, J | 1 |
| Yi, X | 1 |
| Xiao, D | 1 |
| Wang, K | 1 |
1 other study available for 4-phenylbutyric acid and Contracture
| Article | Year |
|---|---|
Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model.
Topics: Adult; Animals; Antioxidants; Cell Differentiation; Contracture; Disease Models, Animal; Endoplasmic | 2018 |