4-phenylbutyric acid has been researched along with Common Variable Immunodeficiency in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Common Variable Immunodeficiency: Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatt, D | 1 |
| Stan, RC | 1 |
| Pinhata, R | 1 |
| Machado, M | 1 |
| Maity, S | 1 |
| Cunningham-Rundles, C | 1 |
| Vogel, C | 1 |
| de Camargo, MM | 1 |
1 other study available for 4-phenylbutyric acid and Common Variable Immunodeficiency
| Article | Year |
|---|---|
Chemical chaperones reverse early suppression of regulatory circuits during unfolded protein response in B cells from common variable immunodeficiency patients.
Topics: B-Lymphocytes; Cells, Cultured; Common Variable Immunodeficiency; Dimethyl Sulfoxide; Endoplasmic Re | 2020 |