4-phenylbutyric acid has been researched along with Cerebral Pseudosclerosis in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumari, N | 1 |
| Kumar, A | 1 |
| Thapa, BR | 1 |
| Modi, M | 1 |
| Pal, A | 1 |
| Prasad, R | 1 |
| van den Berghe, PV | 1 |
| Stapelbroek, JM | 1 |
| Krieger, E | 1 |
| de Bie, P | 1 |
| van de Graaf, SF | 1 |
| de Groot, RE | 1 |
| van Beurden, E | 1 |
| Spijker, E | 1 |
| Houwen, RH | 1 |
| Berger, R | 1 |
| Klomp, LW | 1 |
2 other studies available for 4-phenylbutyric acid and Cerebral Pseudosclerosis
| Article | Year |
|---|---|
Characterization of mutation spectrum and identification of novel mutations in ATP7B gene from a cohort of Wilson disease patients: Functional and therapeutic implications.
Topics: Adolescent; Adult; Case-Control Studies; Cell Line; Cell Survival; Child; Child, Preschool; Cohort S | 2018 |
Reduced expression of ATP7B affected by Wilson disease-causing mutations is rescued by pharmacological folding chaperones 4-phenylbutyrate and curcumin.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Carrier Proteins; Cation Transport | 2009 |