4-phenylbutyric acid has been researched along with Cell Transformation, Viral in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chamcheu, JC | 1 |
| Pihl-Lundin, I | 1 |
| Mouyobo, CE | 1 |
| Gester, T | 1 |
| Virtanen, M | 1 |
| Moustakas, A | 1 |
| Navsaria, H | 1 |
| Vahlquist, A | 1 |
| Törmä, H | 1 |
1 other study available for 4-phenylbutyric acid and Cell Transformation, Viral
| Article | Year |
|---|---|
Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in vitro model for testing new treatments.
Topics: Adolescent; Adult; Cell Line; Cell Transformation, Viral; Epidermis; Hot Temperature; HSP70 Heat-Sho | 2011 |