4-phenylbutyric acid has been researched along with Carcinoma, Non-Small Cell Lung in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, M | 1 |
| Jiang, Y | 1 |
| Wu, H | 1 |
| Shi, W | 1 |
| Lu, G | 1 |
| Cong, D | 1 |
| Liu, K | 1 |
| Song, S | 1 |
| Ren, J | 1 |
| Jin, X | 1 |
| Wu, N | 1 |
| Dai, J | 1 |
| Li, Q | 1 |
| Xiao, X | 1 |
2 other studies available for 4-phenylbutyric acid and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Gambogic Acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced Endoplasmic Reticulum (ER) Stress-Mediated Apoptosis.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Survival; China; Endoplasmic Reticulum C | 2019 |
TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment.
Topics: A549 Cells; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Caspase 3; Caspase 7; Ce | 2017 |