4-phenylbutyric acid has been researched along with Canine Diseases in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, W | 1 |
| Qin, D | 1 |
| Li, B | 1 |
| Zhang, H | 1 |
| Cheng, X | 1 |
| Sun, J | 1 |
| Hua, J | 1 |
| Peng, S | 1 |
1 trial available for 4-phenylbutyric acid and Canine Diseases
| Article | Year |
|---|---|
Immortalized canine adipose-derived mesenchymal stem cells alleviate gentamicin-induced acute kidney injury by inhibiting endoplasmic reticulum stress in mice and dogs.
Topics: Acute Kidney Injury; Animals; Apoptosis; Butylamines; Cells, Cultured; Culture Media; Dog Diseases; | 2021 |